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KMID : 1007420140120020085
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Mood and Emotion
2014 Volume.12 No. 2 p.85 ~ p.94
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Korean Medication Algorithm for Bipolar Disorder 2014 : Maintenance Therapy
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Lee Jung-Goo
Yoon Bo-Hyun
Jeong Jong-Hyun
Kim Moon-Doo
Sohn In-Ki
Shim Se-Hoon
Wang Hee-Ryung
Woo Young-Sup
Jon Duk-In
Seo Jeong-Seok
Shin Young-Chul
Min Kyung-Jun
Bahk Won-Myong
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Abstract
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Objectives : In this study, we aimed to deal with the recommendations for the maintenance treatment for bipolar disorder in Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) 2014.
Method : The questionnaire regarding strategies for maintenance treatment was composed of overall treatment strategies after acute mood episodes, choice of antipsychotics and antidepressants, treatment duration and treatment strategies for breakthrough symptoms.
Results : Regarding the maintenance treatment after acute hypomanic or manic episode in bipolar I or II disorder, combination therapy of mood stabilizer and an atypical antipsychotic agent, monotherapy of mood stabilizer and monotherapy of an atypical antipsychotic agent were chosen as 1st-line treatment. Regarding the maintenance treatment after depressive episode in bipolar I or II disorder, combination therapy of mood stabilizer and an atypical antipsychotic agent, combination of mood stabilizer and lamotrigine, combination of an atypical antipsychotic agent and lamotrigine, mood stabilizer monotherapy, lamotrigine monotherapy, and atypical antipsychotic agent monotherapy were chosen as 1st-line treatment. Preference for atypical antipsychotics and antide-pressants became increased in KMAP-BP 2014 compared to KMAP-BP 2010.
Conclusion : The recommendations for the maintenance treatment in KMAP-BP 2014 seem to reflect current changes in prescription pattern for bipolar disorder.
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KEYWORD
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Bipolar disorder, Maintenance treatment, Algorithm
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